Video
Journal Club Global: Cost effectiveness analyses of PGT-A
The upcoming Journal Club Global will explore a provocative article on the cost effectiveness of PGT-A recently published in Fertility and Sterility. The article provides a systematic literature review of 22 published studies and summarizes the current cost effectiveness evidence on this topic. Infertility treatments are notoriously expensive and often not covered by insurance. PGT is expensive and the clinical efficacy varies in the existing published trials, at least in part due to heterogeneity in study design. Therefore, studying the cost-effectiveness of PGT is a challenging research question which we will explore.
View the Article being discussed: Cost-effectiveness analyses of preimplantation genetic testing
Questions to be addressed:
- What are the key steps to cost effectiveness analyses?
- What are the challenges in assessing cost effectiveness in general and specific to PGT-A?
- How should heterogenous studies be assessed and synthesized systematically?
- What are the main factors driving heterogeneity in the cost effectiveness of PGT-A?
Panelists:
Mina Popovic PhD
Kate Devine MD
Chaim Jalas PhD
Richard Scott, MD HCLD
Diego Marin PhD
Kristine McWilliams MD PhD HCLD
Moderators:
Paul Pirtea, M.D.
Dominique de Ziegler, MD.
Micah J. Hill, DO
More JCG Videos
Journal Club Global: Oral Progestin For Ovulation Suppression During IVF
Live broadcast from the 2024 Midwest Reproductive Symposium
International in Chicago, IL
Journal Club Global en Español: Avances recientes en el tratamiento del síndrome de ovario poliquístico e Infertilidad
Un panel de expertos discutirá dos artículos recientes de Fertility and Sterility que estudian la infertilidad y el síndrome de ovario poliquístico.
Journal Club Global: Cost effectiveness analyses of PGT-A
Infertility treatments can be financially burdensome, often without insurance coverage, making understanding the cost effectiveness of PGT-A crucial.
Journal Club Global: The future of REI Fellowship training: debating opportunities and threats
This exciting collaboration discusses the controversy and future directions for the field of Reproductive Endocrinology and Infertility medicine.
Journal Club Global: Infertility and Subclinical Hypothyroidism
The impact of treating SCH on fertility, obstetric outcomes, and offspring neurocognitive development is debated in the literature.
Journal Club Global: Actualidad En Tratamientos De Fertilidad Para Pacientes Con Endometriosis
Live in Spanish from the 2024 Peruvian Fertility Society Meeting - Lima, Peru
Journal Club Global - Recurrent implantation failure: Reality or statistical mirage?
This exciting new collaboration brings authors and experts to discuss the controversy and future directions for recurrent implantation failure.
Journal Club Global - Evidence based guidelines for PCOS
This virtual event discusses the international guidelines for the assessment and management of PCOS, conducted by the International PCOS Network.
Journal Club Global - Recurrent implantation failure: Reality or statistical mirage?
This exciting new collaboration brings authors and experts to discuss the controversy and future directions for recurrent implantation failure.
Journal Club Global - The Association of Ovarian Reserve and Embryo Aneuploidy
Recent research suggests that the Antimullerian hormone (AMH) may not reliably predict embryo health in both infertility and non-infertility cases.
Journal Club Global - Actualización en la suplementación con progesterona en fase lútea para transferencias de embriones congelados
Efectividad del rescate de progesterona en mujeres que presentan niveles bajos de progesterona circulante alrededor del día de la transferencia de embriones
Journal Club Global - Revisiting the STAR trial: The Fellows debate PGT-A
We are excited to host a debate covering the pros and cons of PGT-A and how new technologies should be validated before clinical implementation.
Journal Club Global: Absolute uterine infertility a Cornelian dilemma: uterine transplantation or surrogacy?
Absolute uterine infertility presents as a Cornelian dilemma for patients and providers.
Journal Club Global: Transferencia de embriones frescos versus congelados: ¿Cuál es la mejor opción
Los resultados de nuevas técnicas de investigación clínica que utilizan información de bancos nacionales de vigilancia médica.
Journal Club Global: IVM in Clinical Practice: An Idea Whose Time Has Come?
In vitro maturation (IVM) has the potential to make IVF cheaper, safer, and more widely accessible to patients with infertility.
Journal Club Global - What is the optimal number of oocytes to reach a live-birth following IVF?
The optimal number of oocytes necessary to expect a live birth following in vitro fertilization remains unclear.
Journal Club Global: Surgical management of endometriosis in women diagnosed with infertility (Spanish language)
Journal Club Global: Natural versus Programmed FET Cycles
Journal Club Global: Moving leiomyoma research from bench to bedside
Journal Club Global: Does diminished ovarian reserve impact embryo aneuploidy or live birth rates?
Journal Club Global: Is PGT-P cutting edge or should we cut it out?
PGT for polygenic risk scoring (PGT-P) is a novel screening strategy of embryos for polygenic conditions and traits.
Journal Club Global: Should everyone freeze oocytes by age 33?
Oocyte cryopreservation is one of the fastest growing areas of reproductive medicine.
Journal Club Global: Management of poor ovarian response
A poor ovarian response to what should otherwise be a successful stimulation cycle presents a clinical conundrum for clinicians.
Journal Club Global: Non-invasive Diagnosis of Endometriosis
One of the most exciting developments in the field of endometriosis is the push towards earlier and less invasive approaches to diagnosis.
Journal Club Global: Prognosis in unexplained RPL
Recurrent pregnancy loss is one of the bigger challenges in the field of reproductive medicine.
Journal Club Global: Evidence for Immunologic Therapies in Women Undergoing ART
Reproductive immunology is perhaps one of the most controversial and promising fields within ART.
Journal Club Global Live from PCRS - Non-Invasive Embryo Selection Techniques
The next great frontier in reproductive medicine is how to non-invasively select an embryo with the highest reproductive potential for transfer.
Journal Club Global Live from PCRS - ICSI for Non-Male Factor Infertility
While intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of male factor infertility, a significant controversy still remains regarding its ubiquitous use in all IVF cycles.
Journal Club Global - To Operate Or Not To Operate: Debating Intramural Fibroids And Fertility
The event will debate the upcoming F&S Fertile Battle “Intramural myomas more than 3 to 4 cm should be surgically removed before IVF”.
Journal Club Global - PGT-A - Can non-invasive approaches based on spent medium analysis
PGT-A by trophectoderm biopsy aims to select available euploid embryos for transfer.
Journal Club Global - Obesity & Reproduction: An Update on Management and Counseling
Obesity can negatively impact reproduction in various ways, including ovulatory and menstrual function, natural fertility and fecundity rates, infertility treatment success rates, infertility treatment safety, and obstetric outcomes
Journal Club Global - Does the Endometrium Play a Major Role in Endometriosis-Associated Infertility
This will be a virtual event in the style of the "Fertile Battle" debate that took place at the 2019 SREI Fellows Symposium
Journal Club Global - Best Practices of High Performing ART Clinics
This Fertility and Sterility Journal Club Global discusses February’s seminal article, “Common practices among consistently high-performing in vitro fertilization programs in the United States: a 10 year update.”
Journal Club Global - Should Fellows Perform Live Embryo Transfers in Fellowship?
Few things are more taboo in reproductive medicine fellowship training than allowing fellows to perform live embryo transfers.
Journal Club Global - Fertilization rate as a novel indicator in ART results
This Journal Club Global discusses a provocative article recently published in Fertility and Sterility, discussing the results of a multicenter retrospective cohort study with the objective to appraise the fertilization rate as a predictive factor for cumulative live birth rate (CLBR).
Journal Club Global Live from ASRM - Optimal Management of the Frozen Embryo Transfer Cycle: Insights From Recent Literature
Three recent papers published in the Fertility and Sterility family of journals, all explore different aspects of optimizing frozen embryo transfer cycles.
Journal Club Global - Are We Approaching Automation in ART?
Some ART diagnostic devices are already available and offer objective tools of evaluation.
Journal Club Global Live from India - Adjuvants in IVF and IVF Add-Ons for the Endometrium
Many adjuvants have been utilized by IVF centers to improve their success rates.
Journal Club Global - Accuracy of Preimplantation Genetic Testing for Aneuploidies
Club Global Académico - ¿Cual debe de ser la primera línea de tratamiento en parejas con infertilidad inexplicable?
Nuestro debate se enfocará en el manejo óptimo de la infertilidad inexplicable, y como el problema debe de ser abordado en Latinoamérica basado en la literatura global reciente.
Journal Club Global - Recurrent Implantation Failures in ART: Myth or Reality?
Fertility and Sterility
F&S Reports
F&S Reports is an open-access journal that publishes peer-reviewed original scientific articles in clinical and translational research that have strong potential to transform clinical practice.
F&S Reviews
F&S Reviews publishes both systematic and comprehensive, authoritative review articles spanning reproductive medicine or science.
F&S Science
F&S Science publishes peer-reviewed original scientific articles in basic, laboratory, and translational research that has strong potential to transform clinical practice.
Fertility and Sterility
Fertility and Sterility® is an international journal for health professionals who treat and investigate problems of infertility and human reproductive disorders.
Journal Club Global
Fertility and Sterility Journal Club Global is an interactive online discussion of a hot topic or seminal article from Fertility and Sterility.
Topic Resources
Journal Club Global: Recent clinical trials in Fertility and Sterility from the Asia Pacific region
Join ASPIRE 2024 for a Journal Club Global on PGT-A and IVF. Learn from top experts discussing recent clinical trial data and pregnancy outcomes View the Video
Coding for an endometrial biopsy/Mock cycle
We had patients request us to bill their insurance for the two monitoring visits and the Endo BX and change the diagnosis code to something that is payable. View the Answer
Fertility and Sterility On Air - Unplugged: March 2024
Topics include: melatonin and implantation (4:38), whole-genome screening of embryos, and bioengineering assisted reproductive technology. Listen to the Episode
Journal Club Global: Cost effectiveness analyses of PGT-A
Infertility treatments can be financially burdensome, often without insurance coverage, making understanding the cost effectiveness of PGT-A crucial. View the Video
Fertility and Sterility On Air - TOC: February 2024
Topics this month include the optimial AMH level in oocyte donors, the role of mean number of DNA breakpoints (MDB) in sperm DNA integrity, and more. Listen to the Episode
Coding PGT requisitions to the PGT lab
Do you have any recommended codes to use for PGT requisitions to the PGT lab? View the Answer
Clinical management of mosaic results from preimplantation genetic testing for aneuploidy of blastocysts: a committee opinion (2023)
This document incorporates studies about mosaic embryo transfer and provides evidence-based considerations for embryos with mosaic results on PGT-A. View the Committee Opinion
Journal Club Global - Revisiting the STAR trial: The Fellows debate PGT-A
We are excited to host a debate covering the pros and cons of PGT-A and how new technologies should be validated before clinical implementation. View the Video
Sperm DNA Fragmentation
Is there a CPT code for HALO DNA Fragmentation for sperm? View the Answer
Results Review
What CPT code is most appropriate to submit for Physician Time to review CCS/PGS/PGD results? View the Answer
ICSI and Embryo Biopsy
How to bill for ICSI or embryo biopsies that occur in different days? View the Answer
Genetic Counseling
Does ASRM have any guidance for how to bill for genetic counseling services provided by a genetic counselor?View the Answer
Embryo Biopsy
Have any new codes been introduced for the lab portion of PGT? View the Answer
Embryo Biopsy Embryologist Travel Costs
Can we bill insurance for the biopsy procedure? Can we bill for travel expenses? View the Answer
Embryo Biopsy PGS Testing
What codes are appropriate for PGS testing? View the Answer
Assisted Zona Hatching
Can assisted hatching and embryo biopsy for PGT-A; PGT-M or PGT-SR be billed during the same cycle? View the Answer
Indications and management of preimplantation genetic testing for monogenic conditions: a committee opinion (2023)
ASRM has updated its opinion on PGT for monogenic conditions, providing guidance on clinical and technical complexities. View the Committee Opinion
Journal Club Global - PGT-A - Can non-invasive approaches based on spent medium analysis
PGT-A by trophectoderm biopsy aims to select available euploid embryos for transfer. View the Video
ASRM müllerian anomalies classification 2021
The Task Force set goals for a new classification and chose to base it on the iconic AFS classification from 1988 because of its simplicity and recognizability. View the Committee Opinion
Journal Club Global - Accuracy of Preimplantation Genetic Testing for Aneuploidies
Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review (2019)
Providers who care for women at risk for hereditary gynecologic cancers must consider the impact of these conditions. View the Joint Statement
Disclosure of sex when incidentally revealed as part of preimplantation genetic testing (PGT): an Ethics Committee opinion (2018)
Clinics may develop a policy to disallow selecting which embryos to transfer based on sex and choose to use only embryo quality as selection criteria. View the Committee Opinion
Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion (2018)
Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. View the Committee Document
Transferring embryos with genetic anomalies detected in preimplantation testing: an Ethics Committee Opinion (2018)
Patient requests for transfer of embryos with genetic anomalies linked to serious health-affecting disorders detected in preimplantation testing are rare but do exist. View the Committee Document
Best practices of ASRM and ESHRE: a journey through reproductive medicine (2012)
ASRM and ESHRE are the two largest societies in the world whose members comprise the major experts and professionals working in reproductive medicine. View the Committee Joint Guideline
