Cyclin N-terminal domain containing 1 (CNTD1) encodes a cyclin-related protein critical for meiosis, but its role in female fertility remains unknown. This study aims to investigate the role of
To report rates and types of mosaic chromosome abnormalities (MCA) identified with preimplantation genetic testing for aneuploidy (PGT-A) via Next Generation Sequencing (NGS) and examine how
To evaluate at a regional level the association between reported IVF utilization of PGT-A in completed transfers and live birth rates by intended retrievals in US-based ART clinics.
Asherman syndrome (AS), characterized by intrauterine adhesions (IUA), is an iatrogenic condition related to uterine instrumentation. The risk of developing IUA is greatest following D&C on
Invasion and migration of extravillous trophoblasts (EVT) into the maternal decidua are essential for immune recognition and the success of human implantation. However, due to ethical concerns
Endometriosis is a gynecological disorder in reproductive-age women characterized by the growth of endometrial tissue outside the uterus. Endometriosis causes infertility and negatively impacts
Ovarian dysfunction poses a major threat to women's health, and mitochondrial oxidative stress is an important mechanism leading to ovarian dysfunction. HIGD1A regulates mitochondrial function
Macrophages and estrogen signaling are both crucial for ovarian function. Mitochondria ensure the energy supply for oocyte vitality, yet over time, oxidative stress and accumulated mitochondrial
Precise spatial and temporal mapping of gene expression is critical to understanding human embryos. Our objective was to combine three-dimensional (3D) targeted in situ RNA sequencing (3DISS)
To compare outcomes from IVF cycles requiring oocyte retrieval offsite of typical location. This research is needed to help increase access to care for medically complex patients ineligible for
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