IMPROVING FERTILIZATION COMPETENCE OF TESTICULAR SPERMATOZOA

Surgically retrieved spermatozoa obtained from azoospermia individuals often exhibit lower fertilization rates (50-60%) compared to ejaculated counterpart (70-80%). In this study, we investigated

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AN INVESTIGATION ON GENETIC ETIOLOGY OF APPARENT IDIOPATHIC PREMATURE OVARIAN FAILURE

Premature ovarian failure (POF) is a complex condition of aberrant ovarian aging due to ovarian dysfunction. It is characterized by amenorrhoea and postmenopausal levels of gonadotropins (FSH) as

PREIMPLANTATION GENETIC TESTING FOR MONOGENIC DISEASE FOR CHALLENGING GENES: EXPERIENCE WITH PKD1 AND NF1

This study assessed the laboratory experience of performing PGT-M for variants in the PKD1 and NF1 genes, associated with polycystic kidney disease type 1 and neurofibromatosis type 1,

PGT-A IN IVF: AN UMBRELLA REVIEW OF REPRODUCTION, MATERNAL AND NEONATAL OUTCOMES, LONG-TERM CHILD HEALTH, AND ECONOMIC IMPACT

Preimplantation genetic testing for aneuploidy (PGT-A) remains controversial regarding its impact on live birth rates, safety, and cost-effectiveness, especially given limited data on long-term

USE OF STORED DNA SAMPLES IN PGT-M TEST CREATION: ONE PGT LABORATORY’S EXPERIENCE

When creating a test for preimplantation genetic testing for monogenic disorders (PGT-M), DNA samples from family members may not be available, meaning other DNA sources may be needed. This is

THE PREVALENCE OF PATHOGENIC VARIANTS IN MEDICALLY ACTIONABLE GENES AMONG INDIVIDUALS WITH IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM/KALLMANN SYNDROME

The objective of our study was to determine if the diagnosis of idiopathic hypogonadotropic hypogonadism (IHH) / Kallmann syndrome (KS) could increase the risk of pathogenic and likely pathogenic

OUTCOME OF A TRISOMY 16 MOSAIC EMBRYO TRANSFER IN A PATIENT WITH ALPORT SYNDROME

To report the management and outcome of a trisomy 16 mosaic embryo transfer (MET) in a patient with Alport syndrome, highlighting the implications of mosaicism in assisted reproductive technology

OPTIMIZING SUCCESS IN PREIMPLANTATION GENETIC TESTING FOR MONOGENIC DISORDERS (PGT-M): KEY PREDICTORS FOR REPRODUCTIVE COUNSELING

To identify clinical and laboratory variables that predict successful reproductive outcomes in patients undergoing preimplantation genetic testing for monogenic disorders (PGT-M).

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