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This narrative review synthesizes existing literature to elucidate the complex interplay between endometriosis and mental health disorders, exploring their prevalence, underlying mechanisms, and
Despite high success rates with the transfer of preimplantation genetic testing for aneuploidy (PGT-A)-tested, euploid embryos, implantation failure can still occur even in patients with a
To report a case of human meiotic recombination illustrated by the use of preimplantation genetic testing for monogenic disorders (PGT-M) in a female patient heterozygous for pathogenic variants
To clinically assess concordance between preimplantation genetic testing-whole-genome sequencing (PGT-WGS) and whole-genome sequencing results from corresponding live-born children, including
To evaluate the efficacy, safety, and pharmacodynamics of linzagolix, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist, in patients with heavy menstrual bleeding (HMB) and pain
Blastocyst-stage transfer is often regarded as superior to cleavage-stage transfer, but the durability of its per-transfer benefit and its effect on cumulative outcomes remain uncertain.
Pening et al. (1) reported a 20-year-old man with 100% acephalic spermatozoa and a novel homozygous nonsense variant in CCDC188, treated with fresh testicular sperm extraction and
Physiologic oocyte activation is initiated by sperm-derived phospholipase C zeta (PLCζ) which results in calcium oscillations crucial for successful fertilization. Defects in oocyte activation
To study the efficacy of a new PGT-M protocol based on SNP informativity and next-generation sequencing (NGS) for the selection of unaffected embryos in a family carrying a 1.33 Mb duplication in
To examine whether dynamic changes in circulating estradiol during ovarian stimulation are associated with the number and maturation status of oocytes recovered in cynomolgus macaques.
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